Postdoctoral Associate - Opthalmology

Summary Dr. Wei Li’s laboratory in the Department of Ophthalmology at the Cullen Eye Institute, Baylor College of Medicine, is seeking a talented and motivated Postdoctoral Associate. The translational research centers on ligandomics—a novel omics technology developed by our group—for drug target discovery and the development of innovative therapies for ocular diseases, that includes glaucoma, diabetic retinopathy, wet age related macular degeneration (AMD), dry AMD, fibrotic and oxidative conditions. This position will focus on investigating disease mechanisms and therapeutic strategies for choroidal neovascularization (CNV) and subretinal fibrosis (SRF). Specifically, the postdoc will functionally validate cellular ligands identified through ligandomics to assess their disease selectivity, binding specificity, biological activity, pathogenic roles, and therapeutic potential. These studies will employ a range of biochemical, cellular, and molecular approaches. The long term goal is to develop effective therapies for CNV and SRF. Postdoctoral Associate with a strong record of scientific productivity, as evidenced by peer reviewed publications, and a strong commitment to research is deisred. Recent recipients of a PhD and/or MD are highly encouraged to apply. Experience in molecular biology, cell biology, protein biochemistry, and/or animal research is strongly desirable. Excellent verbal and written communication skills are required, as the position involves preparing manuscripts and applying for postdoctoral fellowships. The lab offers robust opportunities for career development. Baylor College of Medicine typically follows similar to the NIH stipulated stipend guidelines for Postdoctoral Associates. Job Duties Performs experiments that involves molecular biology, phage display, cell biology, protein expression and purification, protein-protein interaction, immunohistochemistry and animal studies. Performs basic animal research that includes injections, in vivo analyses. Manages mouse colonies to include husbandry, etc. Writes manuscripts and postdoctoral fellowship applications. Organizes lab, reviews inventory and orders supplies. Performs other job-related duties as assigned. Minimum Qualifications MD or Ph.D. in Basic Science, Health Science, or a related field. No experience required. Preferred Qualifications Knowledge of ophthalmology and experience in ophthalmic or animal surgery skills are not necessary but a plus. Demonstrates scientific productivity with peer-reviewed publications and strong commitment to scientific research. Experience in molecular biology, cell biology, protein biochemistry and/or animal research are desired. Excellent verbal and written communication skills.